Characteristics substance mebendazole
Broad spectrum anthelmintic activities. Whitish-yellowish powder, slightly soluble (less than 0.05%) in water, aqueous solutions of mineral acids, alcohol and chloroform, good – in formic acid. The molecular weight of 295.29. Vemox can buy in UK by credit card.
Mode of action – anthelmintic.
It prevents the synthesis of cellular tubulin, breaks glucose utilization and inhibits the formation of ATP in worms.
Slow and incomplete (5-10% of the dose) is absorbed from the gastrointestinal tract. T1 / 2 -. 2.5-5.5 h blood 90% bound to protein. Unevenly distributed to organs. Accumulates in adipose tissue, liver, helminth larvae. Biotransformed in the liver to 2-amino derivative. More than 90% of the dose is excreted unchanged in the feces.
Application of the substance mebendazole
Enterobiasis, Ascariasis, ancylostomiasis, strongyloidiasis, trichocephalosis, multiple nematodes, echinococcosis, taeniasis, alveococcosis, capillariasis, gnathostomiasis, trichinosis, mixed helminthiases. Vemox with fast delivery across the UK.
Hypersensitivity, ulcerative colitis, Crohn’s disease, liver failure, pregnancy, breast-feeding, child up to 2 years.
Pregnancy and breast-feeding
Category effects on the fetus by FDA – C.
At the time of treatment should stop breastfeeding.
Side effects of substance mebendazole
Dizziness, nausea, abdominal pain. When used in high doses for a long time: vomiting, diarrhea, headache, increase in liver transaminases, giperkreatinemiya, leukopenia, anemia, eosinophilia, hair loss, hematuria, cylindruria, allergic reactions (skin rash, urticaria, angioedema). Vemox can be purchased in UK in our online store.